Description
| Antibody Name: | DEFB112 Antibody (PACO20399) |
| Antibody SKU: | PACO20399 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human DEFB112 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20399(DEFB112 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 20 seconds. |
| Background: | Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alph&int∫-defensins, bet&int∫-defensins and thet&int∫-defensins. All bet∫-defensin genes are densely clustered in four to five syntenic chromosomal regions. |
| Synonyms: | defensin, β 112 |
| UniProt Protein Function: | DEFB112: Has antibacterial activity. Belongs to the beta-defensin family.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 6p12.3Cellular Component: cell surfaceBiological Process: defense response to bacterium; innate immune response |
| UniProt Protein Details: | |
| NCBI Summary: | Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q30KQ8 |
| NCBI GenInfo Identifier: | 84028873 |
| NCBI Gene ID: | 245915 |
| NCBI Accession: | Q30KQ8.1 |
| UniProt Secondary Accession: | Q30KQ8,Q8NET0 |
| UniProt Related Accession: | Q30KQ8 |
| Molecular Weight: | 12,991 Da |
| NCBI Full Name: | Beta-defensin 112 |
| NCBI Synonym Full Names: | defensin beta 112 |
| NCBI Official Symbol: | DEFB112 |
| NCBI Official Synonym Symbols: | DEFB-12 |
| NCBI Protein Information: | beta-defensin 112 |
| UniProt Protein Name: | Beta-defensin 112 |
| UniProt Synonym Protein Names: | Beta-defensin 12; DEFB-12; Defensin, beta 112 |
| Protein Family: | Beta-defensin |
| UniProt Gene Name: | DEFB112 |
| UniProt Entry Name: | DB112_HUMAN |
