DEFB104A Antibody (PACO38846)
- SKU:
- PACO38846
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DEFB104A Antibody (PACO38846) |
| Antibody SKU: | PACO38846 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Beta-defensin 104 protein (23-72AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human melanoma using PACO38846 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO38846 at dilution of 1:100. |
| Background: | Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. |
| Synonyms: | Beta-defensin 104 (Beta-defensin 4) (BD-4) (DEFB-4) (hBD-4) (Defensin, β 104), DEFB104A; DEFB104B, DEFB104 DEFB4; |
| UniProt Protein Function: | defensin, beta 4: Has antimicrobial activity. Synergistic effects with lysozyme and DEFB103. Belongs to the beta-defensin family.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 8p23.1Cellular Component: cell surface; extracellular regionBiological Process: defense response to bacterium; innate immune response |
| UniProt Protein Details: | |
| NCBI Summary: | Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q8WTQ1 |
| NCBI GenInfo Identifier: | 118572637 |
| NCBI Gene ID: | 140596 |
| NCBI Accession: | Q8WTQ1.2 |
| UniProt Secondary Accession: | Q8WTQ1,Q496I2, Q496I3, Q496I4 |
| UniProt Related Accession: | Q8WTQ1 |
| Molecular Weight: | Approximately 150 kDa |
| NCBI Full Name: | Beta-defensin 104 |
| NCBI Synonym Full Names: | defensin, beta 104A |
| NCBI Official Symbol: | DEFB104A |
| NCBI Official Synonym Symbols: | BD-4; DEFB4; hBD-4; DEFB-4; DEFB104 |
| NCBI Protein Information: | beta-defensin 104; defensin, beta 4 |
| UniProt Protein Name: | Beta-defensin 104 |
| UniProt Synonym Protein Names: | Beta-defensin 4; BD-4; DEFB-4; hBD-4; Defensin, beta 104 |
| Protein Family: | |
| UniProt Gene Name: | DEFB104A |
| UniProt Entry Name: | D104A_HUMAN |
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