DEFA6 Antibody (PACO15816)
- SKU:
- PACO15816
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DEFA6 Antibody (PACO15816) |
| Antibody SKU: | PACO15816 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human DEFA6 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15816(DEFA6 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several α defensin genes appear to be clustered on chromosome 8. |
| Synonyms: | defensin, α 6, Paneth cell-specific |
| UniProt Protein Function: | Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1. |
| UniProt Protein Details: | |
| NCBI Summary: | Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Oct 2014] |
| UniProt Code: | Q01524 |
| NCBI GenInfo Identifier: | 4503305 |
| NCBI Gene ID: | 1671 |
| NCBI Accession: | NP_001917.1 |
| UniProt Secondary Accession: | Q01524 |
| UniProt Related Accession: | Q01524 |
| Molecular Weight: | |
| NCBI Full Name: | defensin-6 preproprotein |
| NCBI Synonym Full Names: | defensin alpha 6 |
| NCBI Official Symbol: | DEFA6 |
| NCBI Official Synonym Symbols: | DEF6; HD-6 |
| NCBI Protein Information: | defensin-6 |
| UniProt Protein Name: | Defensin-6 |
| UniProt Synonym Protein Names: | Defensin, alpha 6 |
| Protein Family: | Differentially expressed in FDCP |
| UniProt Gene Name: | DEFA6 |
| UniProt Entry Name: |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH
otsB Antibody
Overview Product Name:otsB AntibodyProduct Code:PACO64885Size:50µLTarget Names:otsBSpecies Reactivity:Escherichia coli