DECR1 Monoclonal Antibody [PAT3B2AT] (CPAB0246)
![DECR1 Monoclonal Antibody [PAT3B2AT] (CPAB0246)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58471/63653/assay-genie-box-4__54783.1706535023.jpg?c=1 "DECR1 Monoclonal Antibody [PAT3B2AT] (CPAB0246)")
- SKU:
- CPAB0246
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT3B2AT
- Applications:
- ELISA
- Applications:
- FC
![DECR1 Monoclonal Antibody [PAT3B2AT] (CPAB0246)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58471/63653/assay-genie-box-4__54783.1706535023.jpg?c=1&imbypass=on "DECR1 Monoclonal Antibody [PAT3B2AT] (CPAB0246)")
Description
system_update_alt Datasheet
| Product Name: | DECR1 Antibody |
| Product Sku: | CPAB0246 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human DECR1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human DECR1 protein 35-335 amino acids purified from Ecoli. |
| Clone: | PAT3B2AT. |
| Reactivity: | Human |
| Applications: | ELISA, Flow Cytometry |
| Purification Method: | DECR1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG2b |
| Background: | DECR1 is a mitochondrial protein which exists as a homotetramer and is a member of a family of short-chain dehydrogenases/reductases. DECR1 acts as an auxiliary enzyme of beta-oxidation andt partakes in the metabolism of unsaturated fatty enoyl-CoA esters. in particular, DECR1 uses NADP+ to catalyze the reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA that can subsequently be used as an intermediate in the Krebs cycle. Furthermore, DECR1 is believed to work as a tumor suppressor, possibly downregulating the expression of Neu and slowing the rate of tumorigenesis. |
| Synonyms: | 2,4-dienoyl-CoA reductase, mitochondrial, 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase [NADPH], DECR1, DECR, NADPH, SDR18C1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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