DECR1 Monoclonal Antibody [PAT3B2AT] (CPAB0246)

Name: DECR1 Monoclonal Antibody [PAT3B2AT] (CPAB0246)
SKU: CPAB0246
Availability: OutOfStock

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Metabolism Antibodies 1

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Purification Method:	DECR1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:	IgG2b
Background:	DECR1 is a mitochondrial protein which exists as a homotetramer and is a member of a family of short-chain dehydrogenases/reductases. DECR1 acts as an auxiliary enzyme of beta-oxidation andt partakes in the metabolism of unsaturated fatty enoyl-CoA esters. in particular, DECR1 uses NADP+ to catalyze the reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA that can subsequently be used as an intermediate in the Krebs cycle. Furthermore, DECR1 is believed to work as a tumor suppressor, possibly downregulating the expression of Neu and slowing the rate of tumorigenesis.
Synonyms:	2,4-dienoyl-CoA reductase, mitochondrial, 2,4-dienoyl-CoA reductase [NADPH], 4-enoyl-CoA reductase [NADPH], DECR1, DECR, NADPH, SDR18C1.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Product Name:	DECR1 Antibody
Product Sku:	CPAB0246
Size:	5μg
Host Species:	Mouse
Immunogen:	Anti-human DECR1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human DECR1 protein 35-335 amino acids purified from Ecoli.
Clone:	PAT3B2AT.
Reactivity:	Human
Applications:	ELISA, Flow Cytometry