DDX54 Antibody (PACO00695)
- SKU:
- PACO00695
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DDX54 Antibody |
| Antibody SKU: | PACO00695 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human DDX54. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | DDX54; ATP-dependent RNA helicase DDX54; ATP-dependent RNA helicase DP97; DEAD box RNA helicase 97 kDa; DEAD box protein 54 |
| UniProt Protein Function: | DDX54: Has RNA-dependent ATPase activity. Represses the transcriptional activity of nuclear receptors. Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: EC 3.6.4.13; Helicase; Transcription, coactivator/corepressor; Nucleolus; RNA processing; Nuclear receptor co-regulatorChromosomal Location of Human Ortholog: 12q24.13Cellular Component: membrane; nucleolus; nucleusMolecular Function: estrogen receptor binding; transcription corepressor activity; ATP-dependent RNA helicase activity; ATP binding; receptor bindingBiological Process: RNA processing; estrogen receptor signaling pathway; transcription, DNA-dependent; regulation of transcription, DNA-dependent; RNA metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The nucleolar protein encoded by this gene interacts in a hormone-dependent manner with nuclear receptors, and represses their transcriptional activity. Alternative splice variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TDD1 |
| NCBI GenInfo Identifier: | 164419743 |
| NCBI Gene ID: | 79039 |
| NCBI Accession: | NP_001104792.1 |
| UniProt Secondary Accession: | Q8TDD1,Q86YT8, Q9BRZ1 |
| UniProt Related Accession: | Q8TDD1 |
| Molecular Weight: | 98,666 Da |
| NCBI Full Name: | ATP-dependent RNA helicase DDX54 isoform 1 |
| NCBI Synonym Full Names: | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| NCBI Official Symbol: | DDX54 |
| NCBI Official Synonym Symbols: | DP97 |
| NCBI Protein Information: | ATP-dependent RNA helicase DDX54; DEAD box protein 54; DEAD box helicase 97 KDa; DEAD box RNA helicase 97 kDa; ATP-dependent RNA helicase DP97 |
| UniProt Protein Name: | ATP-dependent RNA helicase DDX54 |
| UniProt Synonym Protein Names: | ATP-dependent RNA helicase DP97; DEAD box RNA helicase 97 kDa; DEAD box protein 54 |
| Protein Family: | ATP-dependent RNA helicase |
| UniProt Gene Name: | DDX54 |
| UniProt Entry Name: | DDX54_HUMAN |
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