DDI2 Antibody (PACO36598)
- SKU:
- PACO36598
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DDI2 Antibody (PACO36598) |
| Antibody SKU: | PACO36598 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein DDI1 homolog 2 protein (1-211AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: DDI2 antibody at 4µg/ml. Lane 1: A431 whole cell lysate. Lane 2: HL60 whole cell lysate. Lane 3: K562 whole cell lysate. Lane 4: Caco-2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 45, 24, 47 kDa. Observed band size: 47 kDa. |
 | Immunohistochemistry of paraffin-embedded human endometrial cancer using PACO36598 at dilution of 1:100. |
| Background: | Aspartic protease that mediates the cleavage of NFE2L1/NRF1 at 'Leu-104', thereby promoting release of NFE2L1/NRF1 from the endoplasmic reticulum membrane. Ubiquitination of NFE2L1/NRF1 is a prerequisite for cleavage, suggesting that DDI2 specifically recognizes and binds ubiquitinated NFE2L1/NRF1. |
| Synonyms: | Protein DDI1 homolog 2 (EC 3.4.23.-), DDI2 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5TDH0 |
| NCBI GenInfo Identifier: | 62955833 |
| NCBI Gene ID: | 84301 |
| NCBI Accession: | NP_115717.3 |
| UniProt Secondary Accession: | Q5TDH0 |
| UniProt Related Accession: | Q5TDH0 |
| Molecular Weight: | 45 kDa |
| NCBI Full Name: | protein DDI1 homolog 2 |
| NCBI Synonym Full Names: | DNA damage inducible 1 homolog 2 |
| NCBI Official Symbol: | DDI2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | protein DDI1 homolog 2 |
| UniProt Protein Name: | Protein DDI1 homolog 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Protein |
| UniProt Gene Name: | DDI2 |
| UniProt Entry Name: | DDI2_HUMAN |
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