Description
Antibody Name: | DCTN4 Antibody (PACO42542) |
Antibody SKU: | PACO42542 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Dynactin subunit 4 protein (2-460AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: HepG2 whole cell lysate, Jurkat whole cell lysate, HEK293 whole cell lysate, SH-SY5Y whole cell lysate. All lanes: DCTN4 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 53, 46, 54 kDa. Observed band size: 53 kDa. |
Background: | Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. |
Synonyms: | Dynactin subunit 4 (Dyn4) (Dynactin subunit p62), DCTN4 |
UniProt Protein Function: | dynactin 4: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; Motor; Microtubule-bindingChromosomal Location of Human Ortholog: 5q33.1Cellular Component: centrosome; cytoplasm; cytoplasmic dynein complex; cytosol; dynactin complex; nucleusMolecular Function: protein binding; protein N-terminus bindingBiological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; ER to Golgi vesicle-mediated transport; nuclear migration |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9UJW0 |
NCBI GenInfo Identifier: | 62900106 |
NCBI Gene ID: | 51164 |
NCBI Accession: | Q9UJW0.1 |
UniProt Secondary Accession: | Q9UJW0,Q8TAN8, B3KWW0, D3DQH0, E5RGT5 |
UniProt Related Accession: | Q9UJW0 |
Molecular Weight: | 53,152 Da |
NCBI Full Name: | Dynactin subunit 4 |
NCBI Synonym Full Names: | dynactin subunit 4 |
NCBI Official Symbol: | DCTN4 |
NCBI Official Synonym Symbols: | P62; DYN4 |
NCBI Protein Information: | dynactin subunit 4 |
UniProt Protein Name: | Dynactin subunit 4 |
UniProt Synonym Protein Names: | Dynactin subunit p62 |
Protein Family: | Dynactin |
UniProt Gene Name: | DCTN4 |
UniProt Entry Name: | DCTN4_HUMAN |
Antibodies |
DCTN4 Antibody (PACO08765) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |