Description
| Antibody Name: | DCTN4 Antibody (PACO42542) |
| Antibody SKU: | PACO42542 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dynactin subunit 4 protein (2-460AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: HepG2 whole cell lysate, Jurkat whole cell lysate, HEK293 whole cell lysate, SH-SY5Y whole cell lysate. All lanes: DCTN4 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 53, 46, 54 kDa. Observed band size: 53 kDa. |
| Background: | Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. |
| Synonyms: | Dynactin subunit 4 (Dyn4) (Dynactin subunit p62), DCTN4 |
| UniProt Protein Function: | dynactin 4: Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton. Belongs to the dynactin subunit 4 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; Motor; Microtubule-bindingChromosomal Location of Human Ortholog: 5q33.1Cellular Component: centrosome; cytoplasm; cytoplasmic dynein complex; cytosol; dynactin complex; nucleusMolecular Function: protein binding; protein N-terminus bindingBiological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; ER to Golgi vesicle-mediated transport; nuclear migration |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9UJW0 |
| NCBI GenInfo Identifier: | 62900106 |
| NCBI Gene ID: | 51164 |
| NCBI Accession: | Q9UJW0.1 |
| UniProt Secondary Accession: | Q9UJW0,Q8TAN8, B3KWW0, D3DQH0, E5RGT5 |
| UniProt Related Accession: | Q9UJW0 |
| Molecular Weight: | 53,152 Da |
| NCBI Full Name: | Dynactin subunit 4 |
| NCBI Synonym Full Names: | dynactin subunit 4 |
| NCBI Official Symbol: | DCTN4 |
| NCBI Official Synonym Symbols: | P62; DYN4 |
| NCBI Protein Information: | dynactin subunit 4 |
| UniProt Protein Name: | Dynactin subunit 4 |
| UniProt Synonym Protein Names: | Dynactin subunit p62 |
| Protein Family: | Dynactin |
| UniProt Gene Name: | DCTN4 |
| UniProt Entry Name: | DCTN4_HUMAN |
| Antibodies |
| DCTN4 Antibody (PACO08765) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
