DcR1 / CD263 Monoclonal Antibody
- SKU:
- CAB23554
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | DcR1 / CD263 Monoclonal Antibody |
| Product Code: | CAB23554 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC3107 |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Jurkat, Raji, A20, MCF7 |
| Cellular Location: | Cell membrane, GPI-anchor, Lipid-anchor |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.
| Immunogen: | Recombinant protein of human DcR1 / CD263. |
| Sequence: | Email for sequence |
| Synonyms: | LIT, DCR1, TRID, CD263, TRAILR3, TRAIL-R3, DCR1-TNFR |
| Calculated MW: | 27kDa |
| Observed MW: | 28kDa |
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