DCHS1 Antibody (PACO63471)
- SKU:
- PACO63471
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DCHS1 Antibody (PACO63471) |
| Antibody SKU: | PACO63471 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Peptide sequence from Human Protocadherin-16 protein (2964-2981AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO63471 diluted at 1:100 and staining in paraffin-embedded human colon cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of SH-SY5Y cells with PACO63471 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. In the heart, has a critical role for proper morphogenesis of the mitral valve, acting in the regulation of cell migration involved in valve formation. |
| Synonyms: | Protocadherin-16 (Cadherin-19) (Cadherin-25) (Fibroblast cadherin-1) (Protein dachsous homolog 1), DCHS1, CDH19 CDH25 FIB1 KIAA1773 PCDH16 |
| UniProt Code: | Q96JQ0 |
| NCBI GenInfo Identifier: | 119589089 |
| NCBI Gene ID: | 8642 |
| NCBI Accession: | EAW68683.1 |
| UniProt Secondary Accession: | Q96JQ0,O15098, |
| UniProt Related Accession: | Q96JQ0 |
| Molecular Weight: | 346,181 Da |
| NCBI Full Name: | dachsous 1 (Drosophila) |
| NCBI Synonym Full Names: | dachsous cadherin-related 1 |
| NCBI Official Symbol: | DCHS1 |
| NCBI Official Synonym Symbols: | FIB1; CDH19; CDH25; CDHR6; PCDH16; VMLDS1 |
| NCBI Protein Information: | protocadherin-16; cadherin-19; cadherin-25; fibroblast cadherin 1; fibroblast cadherin FIB1; protein dachsous homolog 1; cadherin-related family member 6 |
| UniProt Protein Name: | Protocadherin-16 |
| UniProt Synonym Protein Names: | Cadherin-19; Cadherin-25; Fibroblast cadherin-1; Protein dachsous homolog 1 |
| Protein Family: | Protocadherin |
| UniProt Gene Name: | DCHS1 |
| UniProt Entry Name: | PCD16_HUMAN |
Related Products
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost
eutC Antibody
Overview Product Name:eutC AntibodyProduct Code:PACO64709Size:50µLTarget Names:eutCSpecies Reactivity:Escherichia coli
EPHA10 Antibody
Overview Product Name:EPHA10 AntibodyProduct Code:PACO64693Size:50µLTarget Names:EPHA10Species Reactivity:HumanH
otsB Antibody
Overview Product Name:otsB AntibodyProduct Code:PACO64885Size:50µLTarget Names:otsBSpecies Reactivity:Escherichia coli
PCDHA8 Antibody
Overview Product Name:PCDHA8 AntibodyProduct Code:PACO64893Size:50µLTarget Names:PCDHA8Species Reactivity:HumanH