DBF4B Antibody (PACO38330)
- SKU:
- PACO38330
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DBF4B Antibody (PACO38330) |
| Antibody SKU: | PACO38330 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Protein DBF4 homolog B protein (1-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: DBF4B antibody at 4µg/ml. Lane 1: MCF-7 whole cell lysate. Lane 2: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 68, 48, 55, 19 kDa. Observed band size: 48 kDa. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO38330 at dilution of 1:100. |
| Background: | Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle. |
| Synonyms: | Protein DBF4 homolog B (Activator of S phase kinase-like protein 1) (ASK-like protein 1) (Chiffon homolog B) (Dbf4-related factor 1), DBF4B, ASKL1 DRF1 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8NFT6 |
| NCBI GenInfo Identifier: | 22035682 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_663696 |
| UniProt Secondary Accession: | Q8NFT6 |
| UniProt Related Accession: | Q8NFT6 |
| Molecular Weight: | |
| NCBI Full Name: | protein DBF4 homolog B isoform 1 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Protein DBF4 homolog B |
| UniProt Synonym Protein Names: | Activator of S phase kinase-like protein 1; ASK-like protein 1; Chiffon homolog B; Dbf4-related factor 1 |
| Protein Family: | |
| UniProt Gene Name: | DBF4B |
| UniProt Entry Name: | DBF4B_HUMAN |
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