DAO Monoclonal Antibody
- SKU:
- CAB22081
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | DAO Monoclonal Antibody |
| Product Code: | CAB22081 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54988 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:2000-1:20000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, A-549, Mouse brain, Rat brain |
| Cellular Location: | Peroxisome |
This gene encodes the peroxisomal enzyme D-amino acid oxidase. The enzyme is a flavoprotein which uses flavin adenine dinucleotide (FAD) as its prosthetic group. Its substrates include a wide variety of D-amino acids, but it is inactive on the naturally occurring L-amino acids. Its biological function is not known; it may act as a detoxifying agent which removes D-amino acids that accumulate during aging. In mice, it degrades D-serine, a co-agonist of the NMDA receptor. This gene may play a role in the pathophysiology of schizophrenia.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human DAO (NP_001908.3). |
| Sequence: | MRVVV IGAGV IGLST ALCIH ERYHS VLQPL DIKVY ADRFT PLTTT DVAAG LWQPY LSDPN NPQEA DWSQQ TFDYL LSHVH SPNAE NLGLF LISGY NLFHE |
| Synonyms: | DAAO, OXDA, DAMOX |
| Calculated MW: | 39kDa |
| Observed MW: | 39kDa |
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