DAG1 Polyclonal Antibody (CAB21372)
- SKU:
- CAB21372
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | DAG1 Polyclonal Antibody |
| Product Code: | CAB21372 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | SK-BR-3 |
| Cellular Location: | Cell junction, Cell membrane, Cytoplasm, Nucleus, Secreted, Single-pass type I membrane protein, cytoskeleton, extracellular space, nucleoplasm, postsynaptic cell membrane, sarcolemma, synapse |
This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 654-749 of human DAG1 (NP_004384.4). |
| Sequence: | SIVVE WTNNT LPLEP CPKEQ IAGLS RRIAE DDGKP RPAFS NALEP DFKAT SITVT GSGSC RHLQF IPVVP PRRVP SEAPP TEVPD RDPEK SSEDD V |
| Synonyms: | A3a, DAG, AGRNR, 156DAG, MDDGA9, MDDGC7, MDDGC9, LGMDR16 |
| Calculated MW: | 97kDa |
| Observed MW: | 43kDa |
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