Cytokeratin 8 (10A5) Monoclonal Antibody

(No reviews yet) Write a Review
SKU:
CAB24748
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Mouse
Isotype:
IgG
Applications:
WB

Description

Product Name:Cytokeratin 8 (10A5) Monoclonal Antibody
Product Code:CAB24748
Reactivity:Mouse, Rat
Applications:Western blotting
Host Species:Mouse
Purification Method:Affinity purification
Isotype:IgG
Clone No:AMC0654
Reactivity:Mouse, Rat
Tested Applications:WB, ELISA
Key Applications:Western blotting
Recommended Dilution:WB 1:500-1:1000
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Positive Samples:Mouse large intestine, Rat liver
Cellular Location:Cytoplasm, Nucleus, Nucleus matrix, nucleoplasm

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Immunogen:Synthetic Peptide of CK8
Sequence:Email for sequence
Synonyms:K8, KO, CK8, CK-8, CYK8, K2C8, CARD2
Calculated MW:54kDa
Observed MW:60kDa
View AllClose

0 Reviews

View AllClose

Related Products