Cytokeratin 19 (KRT19) Monoclonal Antibody

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SKU:
CAB22427
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
IHC

Description

Product Name:Cytokeratin 19 (KRT19) Monoclonal Antibody
Product Code:CAB22427
Reactivity:Human, Mouse, Rat
Applications:Immunohistochemistry
Host Species:Rabbit
Purification Method:Affinity purification
Isotype:IgG
Clone No:ARC0272
Reactivity:Human, Mouse, Rat
Tested Applications:IHC-P, ELISA
Key Applications:Immunohistochemistry
Recommended Dilution:IHC-P 1:50-1:200
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Cellular Location:apicolateral plasma membrane, costamere, cytoskeleton, cytosol, extracellular exosome, plasma membrane, sarcolemma, terminal web, Z disc

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 301-400 of human Cytokeratin 19 (KRT19) (P08727).
Sequence:RTLQG LEIEL QSQLS MKAAL EDTLA ETEAR FGAQL AHIQA LISGI EAQLG DVRAD SERQN QEYQR LMDIK SRLEQ EIATY RSLLE GQEDH YNNLS ASKVL
Synonyms:K19, CK19, K1CS
Calculated MW:44kDa
Observed MW:Refer to figures
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