CYP2A13 Antibody (PACO00663)
- SKU:
- PACO00663
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CYP2A13 Antibody |
| Antibody SKU: | PACO00663 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the Internal region of human CYP2A13. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CYP2A13; Cytochrome P450 2A13; CYPIIA13 |
| UniProt Protein Function: | CYP2A5: Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N- dimethylaniline, 2'-methoxyacetophenone, N- nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4- (methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity. Belongs to the cytochrome P450 family.Protein type: Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - drug metabolism - cytochrome P450; EC 1.14.14.1; Oxidoreductase; Cofactor and Vitamin Metabolism - retinol; Secondary Metabolites Metabolism - caffeineChromosomal Location of Human Ortholog: 19q13.2Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasmMolecular Function: iron ion binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; heme binding; arachidonic acid epoxygenase activity; steroid hydroxylase activity; oxygen bindingBiological Process: coumarin metabolic process; xenobiotic metabolic process; exogenous drug catabolic process; epoxygenase P450 pathway |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. Although its endogenous substrate has not been determined, it is known to metabolize 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a major nitrosamine specific to tobacco. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16696 |
| NCBI GenInfo Identifier: | 13699809 |
| NCBI Gene ID: | 1553 |
| NCBI Accession: | NP_000757.2 |
| UniProt Secondary Accession: | Q16696,Q53YR8, Q6R569, Q6R570, Q9H2X2 |
| UniProt Related Accession: | Q16696 |
| Molecular Weight: | 56,688 Da |
| NCBI Full Name: | cytochrome P450 2A13 |
| NCBI Synonym Full Names: | cytochrome P450, family 2, subfamily A, polypeptide 13 |
| NCBI Official Symbol: | CYP2A13 |
| NCBI Official Synonym Symbols: | CPAD; CYP2A; CYPIIA13 |
| NCBI Protein Information: | cytochrome P450 2A13; cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 13 |
| UniProt Protein Name: | Cytochrome P450 2A13 |
| UniProt Synonym Protein Names: | CYPIIA13 |
| Protein Family: | Cytochrome |
| UniProt Gene Name: | CYP2A13 |
| UniProt Entry Name: | CP2AD_HUMAN |
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