CYP11A1 Polyclonal Antibody
- SKU:
- CAB21757
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CYP11A1 Polyclonal Antibody |
| Product Code: | CAB21757 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Cellular Location: | Mitochondrion membrane |
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 40-320 of human CYP11A1 (NP_000772.2). |
| Sequence: | ISTRS PRPFN EIPSP GDNGW LNLYH FWRET GTHKV HLHHV QNFQK YGPIY REKLG NVESV YVIDP EDVAL LFKSE GPNPE RFLIP PWVAY HQYYQ RPIGV LLKKS AAWKK DRVAL NQEVM APEAT KNFLP LLDAV SRDFV SVLHR RIKKA GSGNY SGDIS DDLFR FAFES ITNVI FGERQ GMLEE VVNPE AQRFI DAIYQ MFHTS VPMLN LPPDL FRLFR TKTWK DHVAA WDVIF SKADI YTQNF YWELR QKGSV HHDYR GILYR LLGDS KMSFE DIKAN V |
| Synonyms: | CYP11A, CYPXIA1, P450SCC |
| Calculated MW: | 60kDa |
| Observed MW: | Refer to figures |
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