CXXC5 Antibody (PACO36738)
- SKU:
- PACO36738
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CXXC5 Antibody (PACO36738) |
| Antibody SKU: | PACO36738 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human CXXC-type zinc finger protein 5 protein (1-227AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human brain tissue using PACO36738 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO36738 at dilution of 1:100. |
| Background: | May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and RBPJ. |
| Synonyms: | CXXC-type zinc finger protein 5 (CF5) (Putative MAPK-activating protein PM08) (Putative NF-kappa-B-activating protein 102) (Retinoid-inducible nuclear factor) (RINF), CXXC5 |
| UniProt Protein Function: | CXXC5: May indirectly participate in activation of the NF- kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells. Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 5q31.2Cellular Component: cytoplasm; nucleoplasmMolecular Function: protein binding; sequence-specific DNA binding; signal transducer activity; transcription factor bindingBiological Process: negative regulation of transcription from RNA polymerase II promoter; positive regulation of I-kappaB kinase/NF-kappaB cascade |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a retinoid-inducible nuclear protein containing a CXXC-type zinc finger motif. The encoded protein is involved in myelopoiesis, is required for DNA damage-induced p53 activation, regulates the differentiation of C2C12 myoblasts into myocytes, and negatively regulates cutaneous wound healing. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015] |
| UniProt Code: | Q7LFL8 |
| NCBI GenInfo Identifier: | 167011303 |
| NCBI Gene ID: | 51523 |
| NCBI Accession: | Q7LFL8.1 |
| UniProt Secondary Accession: | Q7LFL8,Q8TB79, Q9NV51, Q9P0S8, B3KND0, C8CBA8 |
| UniProt Related Accession: | Q7LFL8 |
| Molecular Weight: | 24,072 Da |
| NCBI Full Name: | CXXC-type zinc finger protein 5 |
| NCBI Synonym Full Names: | CXXC finger protein 5 |
| NCBI Official Symbol: | CXXC5 |
| NCBI Official Synonym Symbols: | CF5; WID; RINF; HSPC195 |
| NCBI Protein Information: | CXXC-type zinc finger protein 5 |
| UniProt Protein Name: | CXXC-type zinc finger protein 5 |
| UniProt Synonym Protein Names: | Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; Retinoid-inducible nuclear factor; RINF |
| Protein Family: | CXXC-type zinc finger protein |
| UniProt Gene Name: | CXXC5 |
| UniProt Entry Name: | CXXC5_HUMAN |
Related Products
Human CXXC5 (CXXC-Type Zinc Finger Protein 5) ELISA Kit (HUFI03403)
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीकी
Human TP53 antibody(p53 antibody) ELISA Kit
system_update_altDatasheet - तकनीकी मैनुअलsystem_update_altMSDS - तकनीक
OSTN Antibody
Overview Product Name:OSTN AntibodyProduct Code:PACO64881Size:50µLTarget Names:OSTNSpecies Reactivity:HumanHost
CYP2A13 Antibody
Overview Product Name:CYP2A13 AntibodyProduct Code:PACO64657Size:50µLTarget Names:CYP2A13Species Reactivity:Human, Mouse
OR13C8 Antibody
Overview Product Name:OR13C8 AntibodyProduct Code:PACO64869Size:50µLTarget Names:OR13C8Species Reactivity:HumanH
TTC14 Antibody
Overview Product Name:TTC14 AntibodyProduct Code:PACO64997Size:50µLTarget Names:TTC14Species Reactivity:HumanHos
SIM1 Antibody
Overview Product Name:SIM1 AntibodyProduct Code:PACO64949Size:50µLTarget Names:SIM1Species Reactivity:HumanHost