Description
| Product Name: | CXCR5/CD185 Monoclonal Antibody |
| Product Code: | CAB23989 |
| Reactivity: | Human, Mouse |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC62169 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Daudi, Raji |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
This gene encodes a multi-pass membrane protein that belongs to the CXC chemokine receptor family. It is expressed in mature B-cells and Burkitt's lymphoma. This cytokine receptor binds to B-lymphocyte chemoattractant (BLC), and is involved in B-cell migration into B-cell follicles of spleen and Peyer patches. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-47 of human CXCR5 (NP_001707.1) |
| Sequence: | MNYPL TLEMD LENLE DLFWE LDRLD NYNDT SLVEN HLCPA TEGPL MA |
| Synonyms: | BLR1, CD185, MDR15 |
| Calculated MW: | 42kDa |
| Observed MW: | 42kDa |