Description
| Product Name: | CXCL10/IP-10 Monoclonal Antibody |
| Product Code: | CAB21986 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC5116-05 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IP, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunoprecipitation |
| Recommended Dilution: | WB 1:2000-1:20000, IHC-P 1:50-1:200, IP 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | THP-1(THP-1 cells were treated by LPS for 6 hours, Brefeldin A for 3 hours and IFNγ (50ng/ml) for 8 hours of stimulation.) |
| Cellular Location: | Secreted |
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection.
| Immunogen: | Recombinant protein of human CXCL10/IP-10. |
| Sequence: | Email for sequence |
| Synonyms: | C7, IFI10, INP10, IP-10, crg-2, mob-1, SCYB10, gIP-10 |
| Calculated MW: | 11kDa |
| Observed MW: | 11kDa |