Name: Cxcl1 Antibody (PACO32672)
SKU: PACO32672
Availability: OutOfStock

Antibody Name:	Cxcl1 Antibody (PACO32672)
Antibody SKU:	PACO32672
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Mouse
Immunogen:	Recombinant Mouse Growth-regulated α protein (29-96AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:	Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation By similarity. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. KC(5-72) shows a highly enhanced hematopoietic activity.
Synonyms:	Growth-regulated α protein (C-X-C motif chemokine 1) (Platelet-derived growth factor-inducible protein KC) (Secretory protein N51) [Cleaved into: KC(5-72) (Hematopoietic synergistic factor) (HSF) (KC-T)], Cxcl1, Gro Gro1 Mgsa Scyb1

UniProt Protein Function:	CXCL2: Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. Belongs to the intercrine alpha (chemokine CxC) family.
UniProt Protein Details:	Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide Cellular Component: extracellular space; cell; extracellular region; cytosol Molecular Function:growth factor activity; chemokine activity; CXCR chemokine receptor binding; cytokine activity Biological Process: neutrophil chemotaxis; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; response to molecule of bacterial origin; positive regulation of superoxide release; positive regulation of potassium ion transport; response to lipopolysaccharide; immune response; positive regulation of leukocyte chemotaxis; inflammatory response; acute inflammatory response; regulation of cell proliferation
NCBI Summary:	This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This secretory protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils. In mouse, deficiency of this gene is associated with colitis and with defects in immune cell recruitment to the lung. [provided by RefSeq, Apr 2013]
UniProt Code:	P12850
NCBI GenInfo Identifier:	121623
NCBI Gene ID:	14825
NCBI Accession:	P12850.1
UniProt Related Accession:	P12850
Molecular Weight:	10,254 Da
NCBI Full Name:	Growth-regulated alpha protein
NCBI Synonym Full Names:	chemokine (C-X-C motif) ligand 1
NCBI Official Symbol:	Cxcl1
NCBI Official Synonym Symbols:	KC; Fsp; N51; gro; Gro1; Mgsa; Scyb1
NCBI Protein Information:	growth-regulated alpha protein; KC/GR)-alpha; KC/GRO-alpha; GRO1 oncogene; alpha-chemokine; secretory protein N51; C-X-C motif chemokine 1; platelet-derived growth factor-inducible protein KC
UniProt Protein Name:	Growth-regulated alpha protein
UniProt Synonym Protein Names:	C-X-C motif chemokine 1; Platelet-derived growth factor-inducible protein KC; Secretory protein N51Cleaved into the following chain:KC(5-72)Alternative name(s):Hematopoietic synergistic factor; HSF; KC-T
Protein Family:	KCNQ1 downstream neighbor protein
UniProt Gene Name:	Cxcl1
UniProt Entry Name:	GROA_MOUSE