Description
Antibody Name: | CUTC Antibody (PACO58508) |
Antibody SKU: | PACO58508 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Copper homeostasis protein cutC homolog protein (1-64AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO58508 diluted at 1:400 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | Immunofluorescence staining of Hela cells with PACO58508 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | IHC image of PACO58508 diluted at 1:400 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
Background: | May play a role in copper homeostasis. Can bind one Cu(1+) per subunit. |
Synonyms: | Copper homeostasis protein cutC homolog, CUTC |
UniProt Protein Function: | CUTC: a copper binding protein associated with copper homeostasis and transport. Widely expressed in human tissues. Its nuclear and cytoplasmic distribution suggests that it may be a nucleocytoplasmic copper ion shuttle protein.Protein type: CarrierChromosomal Location of Human Ortholog: 10q24.2Cellular Component: cytoplasm; nucleolus; nucleusMolecular Function: copper ion binding; protein bindingBiological Process: protein tetramerization |
UniProt Protein Details: | |
NCBI Summary: | Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper (Gupta et al., 1995 [PubMed 7635807]; Li et al., 2005 [PubMed 16182249]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9NTM9 |
NCBI GenInfo Identifier: | 54035909 |
NCBI Gene ID: | 51076 |
NCBI Accession: | Q9NTM9.1 |
UniProt Secondary Accession: | Q9NTM9,Q5TCZ8, Q9Y321 |
UniProt Related Accession: | Q9NTM9 |
Molecular Weight: | 29,341 Da |
NCBI Full Name: | Copper homeostasis protein cutC homolog |
NCBI Synonym Full Names: | cutC copper transporter |
NCBI Official Symbol: | CUTC |
NCBI Official Synonym Symbols: | CGI-32 |
NCBI Protein Information: | copper homeostasis protein cutC homolog |
UniProt Protein Name: | Copper homeostasis protein cutC homolog |
UniProt Synonym Protein Names: | |
Protein Family: | CutC-like protein |
UniProt Gene Name: | CUTC |
UniProt Entry Name: | CUTC_HUMAN |
Antibodies |
CUTC Antibody (PACO08680) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |