CUTC Antibody (PACO58508)
- SKU:
- PACO58508
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CUTC Antibody (PACO58508) |
| Antibody SKU: | PACO58508 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Copper homeostasis protein cutC homolog protein (1-64AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO58508 diluted at 1:400 and staining in paraffin-embedded human gastric cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of Hela cells with PACO58508 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | IHC image of PACO58508 diluted at 1:400 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | May play a role in copper homeostasis. Can bind one Cu(1+) per subunit. |
| Synonyms: | Copper homeostasis protein cutC homolog, CUTC |
| UniProt Protein Function: | CUTC: a copper binding protein associated with copper homeostasis and transport. Widely expressed in human tissues. Its nuclear and cytoplasmic distribution suggests that it may be a nucleocytoplasmic copper ion shuttle protein.Protein type: CarrierChromosomal Location of Human Ortholog: 10q24.2Cellular Component: cytoplasm; nucleolus; nucleusMolecular Function: copper ion binding; protein bindingBiological Process: protein tetramerization |
| UniProt Protein Details: | |
| NCBI Summary: | Members of the CUT family of copper transporters are associated with copper homeostasis and are involved in the uptake, storage, delivery, and efflux of copper (Gupta et al., 1995 [PubMed 7635807]; Li et al., 2005 [PubMed 16182249]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9NTM9 |
| NCBI GenInfo Identifier: | 54035909 |
| NCBI Gene ID: | 51076 |
| NCBI Accession: | Q9NTM9.1 |
| UniProt Secondary Accession: | Q9NTM9,Q5TCZ8, Q9Y321 |
| UniProt Related Accession: | Q9NTM9 |
| Molecular Weight: | 29,341 Da |
| NCBI Full Name: | Copper homeostasis protein cutC homolog |
| NCBI Synonym Full Names: | cutC copper transporter |
| NCBI Official Symbol: | CUTC |
| NCBI Official Synonym Symbols: | CGI-32 |
| NCBI Protein Information: | copper homeostasis protein cutC homolog |
| UniProt Protein Name: | Copper homeostasis protein cutC homolog |
| UniProt Synonym Protein Names: | |
| Protein Family: | CutC-like protein |
| UniProt Gene Name: | CUTC |
| UniProt Entry Name: | CUTC_HUMAN |
| Antibodies |
| CUTC Antibody (PACO08680) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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