Ctsk Antibody (PACO26033)
- SKU:
- PACO26033
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Ctsk Antibody (PACO26033) |
| Antibody SKU: | PACO26033 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:10-1:100 |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Cathepsin K protein (115-329AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO26033 at dilution of 1:20. |
| Background: | Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid, pH. May play an important role in extracellular matrix degradation By similarity. |
| Synonyms: | Cathepsin K (EC 3.4.22.38), Ctsk |
| UniProt Protein Function: | CTSK: Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Defects in CTSK are the cause of pycnodysostosis (PKND). PKND is an autosomal recessive osteochondrodysplasia characterized by osteosclerosis and short stature. Belongs to the peptidase C1 family. |
| UniProt Protein Details: | Protein type:EC 3.4.22.38; Protease Cellular Component: cytoplasm; extracellular space; lysosome Molecular Function:collagen binding; cysteine-type endopeptidase activity; cysteine-type peptidase activity; fibronectin binding; proteoglycan binding Biological Process: bone resorption; collagen catabolic process; intramembranous ossification; proteolysis; proteolysis involved in cellular protein catabolic process |
| NCBI Summary: | putative protease; human homolog displays endoprotease activity and is associated with pycnodysostosis when mutated [RGD, Feb 2006] |
| UniProt Code: | O35186 |
| NCBI GenInfo Identifier: | 12585195 |
| NCBI Gene ID: | 29175 |
| NCBI Accession: | O35186.1 |
| UniProt Related Accession: | O35186 |
| Molecular Weight: | 36,791 Da |
| NCBI Full Name: | Cathepsin K |
| NCBI Synonym Full Names: | cathepsin K |
| NCBI Official Symbol: | Ctsk |
| NCBI Protein Information: | cathepsin K |
| UniProt Protein Name: | Cathepsin K |
| Protein Family: | Cathepsin |
| UniProt Gene Name: | Ctsk |
| UniProt Entry Name: | CATK_RAT |
| ELISA Kits |
| Rat Cathepsin K ELISA Kit |
| Rat CTSK (Cathepsin K) CLIA Kit (RTES00102) |
| Rat Cathepsin K (Ctsk) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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