Name: Ctsg Antibody (PACO26029)
SKU: PACO26029
Availability: OutOfStock

Antibody Name:	Ctsg Antibody (PACO26029)
Antibody SKU:	PACO26029
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA
Recommended Dilutions:
Species Reactivity:	Mouse
Immunogen:	Recombinant Mouse Cathepsin G protein (21-261AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Background:	This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis.
Synonyms:	Cathepsin G (EC 3.4.21.20) (Vimentin-specific protease) (VSP), Ctsg

UniProt Protein Function:	CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family.
UniProt Protein Details:	Protein type:Motility/polarity/chemotaxis; EC 3.4.21.20; Protease Cellular Component: cytoplasm; extracellular matrix; extracellular space; intermediate filament; intracellular membrane-bound organelle; membrane; nucleus; plasma membrane; secretory granule Molecular Function:heparin binding; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity Biological Process: defense response to fungus; defense response to Gram-positive bacterium; immune response; positive regulation of immune response; protein amino acid phosphorylation; protein processing; proteolysis; response to lipopolysaccharide
NCBI Summary:	This gene encodes a member of the peptidase S1 (chymotrypsin) family of serine endopeptidases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product appears to play a role in host defense, including inflammation and antigen processing. Homozygous knockout mice for this gene exhibit enhanced susceptibility to bacterial and fungal infection. [provided by RefSeq, Aug 2015]
UniProt Code:	P28293
NCBI GenInfo Identifier:	6681083
NCBI Gene ID:	13035
NCBI Accession:	NP_031826.1
UniProt Related Accession:	P28293
Molecular Weight:	42.9 kDa
NCBI Full Name:	cathepsin G preproprotein
NCBI Synonym Full Names:	cathepsin G
NCBI Official Symbol:	Ctsg
NCBI Official Synonym Symbols:	VSP; CatG
NCBI Protein Information:	cathepsin G
UniProt Protein Name:	Cathepsin G
UniProt Synonym Protein Names:	Vimentin-specific protease; VSP
Protein Family:	Cathepsin
UniProt Gene Name:	Ctsg
UniProt Entry Name:	CATG_MOUSE