CTLA4 Monoclonal Antibody [PAT4F2AT] (CPAB0074)

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SKU:
CPAB0074
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT4F2AT
Applications:
WB
Applications:
ELISA

Description

system_update_alt Datasheet
Product Name:CTLA4 Antibody
Product Sku:CPAB0074
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CTLA4 mAb, clone PAT4F2AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CTLA4 protein 36-161 amino acids purified from Ecoli.
Clone:PAT4F2AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:CTLA4 antibody was purified by protein-A affinity chromatography.
Isotype:IgG1
Background:CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases.
Synonyms:GSE, CD152, IDDM12, CELIAC3, CTLA-4.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
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