![CTLA4 Monoclonal Antibody [PAT4F2AT] (CPAB0074)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58302/63484/ctla4-monoclonal-antibody-pat4f2at-cpab0074__17618__25839.1706534964.jpg?c=1?imbypass=on "CTLA4 Monoclonal Antibody [PAT4F2AT] (CPAB0074)")
Description
system_update_alt Datasheet
| Product Name: | CTLA4 Antibody |
| Product Sku: | CPAB0074 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human CTLA4 mAb, clone PAT4F2AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CTLA4 protein 36-161 amino acids purified from Ecoli. |
| Clone: | PAT4F2AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA |
| Purification Method: | CTLA4 antibody was purified by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
| Synonyms: | GSE, CD152, IDDM12, CELIAC3, CTLA-4. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
![CTLA4 Monoclonal Antibody [PAT4F2AT] (CPAB0074)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58302/63484/ctla4-monoclonal-antibody-pat4f2at-cpab0074__17618__25839.1706534964.jpg?c=1 "CTLA4 Monoclonal Antibody [PAT4F2AT] (CPAB0074)")
