Description
Product Name: | CTIP2/BCL11B Polyclonal Antibody |
Product Code: | CAB21767 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
Cellular Location: | neuron projection, nucleus |
This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 190-310 of human CTIP2/BCL11B (NP_612808.1). |
Sequence: | PVSGD GTQGE GQTEA PFGCQ CQLSG KDEPS SYICT TCKQP FNSAW FLLQH AQNTH GFRIY LEPGP ASSSL TPRLT IPPPL GPEAV AQSPL MNFLG DSNPF NLLRM TGPIL RDHPG FGEGR L |
Synonyms: | ATL1, RIT1, CTIP2, IMD49, CTIP-2, IDDFSTA, SMARCM2, ZNF856B, ATL1-beta, ATL1-alpha, ATL1-delta, ATL1-gamma, hRIT1-alpha |
Calculated MW: | 96kDa |
Observed MW: | Refer to figures |