Ctgf Antibody (PACO51454)

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SKU:
PACO51454
Product Type:
Antibody
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Applications:
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Ctgf Antibody (PACO51454)
Antibody SKU:PACO51454
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:200-1:2000
Species Reactivity:Mouse, Rat
Immunogen:Recombinant Mouse Connective tissue growth factor protein (26-344AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern Blot. Positive WB detected in: Rat skeletal muscle tissue. All lanes: Ctgf antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa..
Background:Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity).
Synonyms:Connective tissue growth factor (CCN family member 2) (Hypertrophic chondrocyte-specific protein 24) (Protein FISP-12), Ctgf, Ccn2 Fisp-12 Fisp12 Hcs24
UniProt Protein Function:CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted; Cell adhesion

Cellular Component: cell cortex; cis-Golgi network; cytosol; extracellular region; extracellular space; Golgi apparatus; intracellular membrane-bound organelle; perinuclear region of cytoplasm; proteinaceous extracellular matrix

Molecular Function:fibronectin binding; growth factor activity; heparin binding; insulin-like growth factor binding; integrin binding; protein C-terminus binding

Biological Process: angiogenesis; cartilage condensation; cell adhesion; cell differentiation; cell migration; cell-cell signaling; cell-matrix adhesion; fibroblast growth factor receptor signaling pathway; integrin-mediated signaling pathway; lung development; ossification; positive regulation of caspase activity; positive regulation of cell activation; positive regulation of cell differentiation; positive regulation of cell proliferation; positive regulation of collagen biosynthetic process; positive regulation of JNK cascade; positive regulation of protein amino acid phosphorylation; positive regulation of stress fiber formation; regulation of cell growth; regulation of chondrocyte differentiation; tissue homeostasis

UniProt Code:P29268
NCBI GenInfo Identifier:171846283
NCBI Gene ID:14219
NCBI Accession:NP_034347.2
UniProt Secondary Accession:P29268,Q922U0, G5E830,
UniProt Related Accession:P29268
Molecular Weight:53.5 kDa
NCBI Full Name:connective tissue growth factor
NCBI Synonym Full Names:connective tissue growth factor
NCBI Official Symbol:Ctgf  
NCBI Official Synonym Symbols:Ccn2; Hcs24; Fisp12; fisp-12  
NCBI Protein Information:connective tissue growth factor
UniProt Protein Name:Connective tissue growth factor
UniProt Synonym Protein Names:CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Protein FISP-12
Protein Family:Connective tissue growth factor
UniProt Gene Name:Ctgf  
UniProt Entry Name:CTGF_MOUSE
ELISA Kits
Mouse CTGF / Connective tissue growth factor ELISA Kit
Mouse CTGF (Connective Tissue Growth Factor) CLIA Kit (MOES00195)
Mouse Connective tissue growth factor (Ctgf) ELISA Kit
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
Recommended Products
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011)
Anti-HRP-conjugated Beta Actin Antibody (CABC028)
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system_update_altDatasheetHuman CTGF/CCN2 Recombinant Protein CTGF belongs to the CCN (CTGF/Cyr61/Cef10/NOVH) protein family; which is comprised of six secreted proteins that reside in the extrac