CTDSP2 Antibody (PACO08655)
- SKU:
- PACO08655
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CTDSP2 Antibody (PACO08655) |
| Antibody SKU: | PACO08655 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human CTDSP2 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2;CTDSP2;OS4;PSR2;SCP2 ; |
| UniProt Protein Function: | CTDSP2: Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.Protein type: Nuclear receptor co-regulator; EC 3.1.3.16; PhosphataseChromosomal Location of Human Ortholog: 12q14.1Cellular Component: nucleoplasmMolecular Function: protein binding; metal ion binding; CTD phosphatase activityBiological Process: unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; negative regulation of protein amino acid phosphorylation; unfolded protein response; protein amino acid dephosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O14595 |
| NCBI GenInfo Identifier: | 55584145 |
| NCBI Gene ID: | 10106 |
| NCBI Accession: | O14595.2 |
| UniProt Secondary Accession: | O14595,Q53ZR2, Q6NZY3, Q9UEX1, A8K5H4 |
| UniProt Related Accession: | O14595 |
| Molecular Weight: | |
| NCBI Full Name: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 |
| NCBI Synonym Full Names: | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 |
| NCBI Official Symbol: | CTDSP2 |
| NCBI Official Synonym Symbols: | OS4; PSR2; SCP2 |
| NCBI Protein Information: | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; NLI-interacting factor 2; conserved gene amplified in osteosarcoma; nuclear LIM interactor-interacting factor 2; protein OS-4; small C-terminal domain phosphatase 2; small CTD phosphatase 2 |
| UniProt Protein Name: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 |
| UniProt Synonym Protein Names: | Nuclear LIM interactor-interacting factor 2; NLI-interacting factor 2; Protein OS-4; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2; SCP2 |
| Protein Family: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase |
| UniProt Gene Name: | CTDSP2 |
| UniProt Entry Name: | CTDS2_HUMAN |
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