CTDNEP1 Antibody (PACO31964)
- SKU:
- PACO31964
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CTDNEP1 Antibody (PACO31964) |
| Antibody SKU: | PACO31964 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human CTD nuclear envelope phosphatase 1 protein (3-244AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO31964 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO31964 at dilution of 1:100. |
| Synonyms: | CTD nuclear envelope phosphatase 1 (EC 3.1.3.16) (Serine/threonine-protein phosphatase dullard), CTDNEP1, DULLARD |
| UniProt Protein Function: | DULLARD: Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol. May antagonize BMP signaling. Belongs to the dullard family.Protein type: EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor); Endoplasmic reticulum; Membrane protein, integralChromosomal Location of Human Ortholog: 17p13Cellular Component: cytoplasm; endoplasmic reticulum membrane; nuclear envelope; nuclear membraneMolecular Function: protein binding; protein serine/threonine phosphatase activityBiological Process: mitotic nuclear envelope disassembly; nuclear membrane organization and biogenesis; protein amino acid dephosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | O95476 |
| NCBI GenInfo Identifier: | 262527541 |
| NCBI Gene ID: | 23399 |
| NCBI Accession: | O95476.2 |
| UniProt Secondary Accession: | O95476,Q96GQ9, D3DTN7 |
| UniProt Related Accession: | O95476 |
| Molecular Weight: | 28,377 Da |
| NCBI Full Name: | CTD nuclear envelope phosphatase 1 |
| NCBI Synonym Full Names: | CTD nuclear envelope phosphatase 1 |
| NCBI Official Symbol: | CTDNEP1 |
| NCBI Official Synonym Symbols: | NET56; DULLARD; HSA011916 |
| NCBI Protein Information: | CTD nuclear envelope phosphatase 1 |
| UniProt Protein Name: | CTD nuclear envelope phosphatase 1 |
| UniProt Synonym Protein Names: | Serine/threonine-protein phosphatase dullard |
| Protein Family: | CTD nuclear envelope phosphatase |
| UniProt Gene Name: | CTDNEP1 |
| UniProt Entry Name: | CNEP1_HUMAN |
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