CST11 Antibody (PACO00674)
- SKU:
- PACO00674
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CST11 Antibody |
| Antibody SKU: | PACO00674 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human |
| Immunogen: | synthesized peptide derived from the C-terminal region of human Cystatin 11. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CST11; CST8L; Cystatin-11 |
| UniProt Protein Function: | CST11: Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization. Belongs to the cystatin family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 20p11.21Cellular Component: cytoplasm; nucleusMolecular Function: cysteine protease inhibitor activityBiological Process: defense response to bacterium |
| UniProt Protein Details: | |
| NCBI Summary: | The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E. coli. Alternative splicing yields two variants encoding distinct isoforms. [provided by RefSeq, Sep 2014] |
| UniProt Code: | Q9H112 |
| NCBI GenInfo Identifier: | 18644732 |
| NCBI Gene ID: | 140880 |
| NCBI Accession: | NP_543020.2 |
| UniProt Secondary Accession: | Q9H112,Q0VAF2, Q0VAF3, Q8WXU5, Q8WXU6, Q9H113 |
| UniProt Related Accession: | Q9H112 |
| Molecular Weight: | 12,285 Da |
| NCBI Full Name: | cystatin-11 isoform 2 |
| NCBI Synonym Full Names: | cystatin 11 |
| NCBI Official Symbol: | CST11 |
| NCBI Official Synonym Symbols: | SC13; CST8L; CTES2; dJ322G13.6 |
| NCBI Protein Information: | cystatin-11 |
| UniProt Protein Name: | Cystatin-11 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Cystatin |
| UniProt Gene Name: | CST11 |
| UniProt Entry Name: | CST11_HUMAN |
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