Description
system_update_alt Datasheet
Product Name: | CSNK2A1 Antibody |
Product Sku: | CPAB0131 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CSNK2A1 mAb is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CSNK2A1 amino acids 1-391 purified from Ecoli. |
Clone: | P3G1AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | CSNK2A1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG1 |
Background: | The Casein kinase 2 (EC 2.7.11.1) is a serine/threonine-selective protein kinase that is a tetramer of two alpha subunits and two beta subunits. The alpha subunits have the catalytic kinase domain. Casein kinase 2 has been implicated in cell cycle control, DNA repair, regulation of the circadian rhythm and other cellular processes. Casein kinase 2 activity has been reported to be activated following Wnt signaling pathway activation. A Pertussis toxin-sensitive G protein and Disheveled appear to be an intermediary between Wnt-mediated activation of the Frizzled receptor and activation of casein kinase 2. Mice that lack casein kinase 2 alpha prime have a defect in the morphology of developing sperm. |
Synonyms: | Casein kinase II subunit alpha, EC 2.7.11.1, CK II, CK2A1, CKII alpha, CSNK2A1, PKCK2, CSK21. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |