CSH2 Antibody (PACO51450)
- SKU:
- PACO51450
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CSH2 Antibody (PACO51450) |
| Antibody SKU: | PACO51450 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Chorionic somatomammotropin hormone 2 protein (27-217AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: Mouse heart tissue, Mouse kidney tissue. All lanes: CSH2 antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 25, 19, 14 kDa. Observed band size: 25 kDa.. |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO51450 at dilution of 1:100. |
| Background: | Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. |
| Synonyms: | Chorionic somatomammotropin hormone 2 (Choriomammotropin) (Lactogen) (Placental lactogen) (PL), CSH2 |
| UniProt Protein Function: | CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 17q24.2Cellular Component: extracellular regionMolecular Function: metal ion binding; hormone activity |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P0DML3 |
| NCBI GenInfo Identifier: | 387024 |
| NCBI Gene ID: | 1443 |
| NCBI Accession: | AAA98747.1 |
| UniProt Secondary Accession: | P0DML3,P01243, Q0VDB1, Q14407 |
| UniProt Related Accession: | P0DML3 |
| Molecular Weight: | 13,914 Da |
| NCBI Full Name: | placental lactogen hormone |
| NCBI Synonym Full Names: | chorionic somatomammotropin hormone 2 |
| NCBI Official Symbol: | CSH2 |
| NCBI Official Synonym Symbols: | PL; CSB; CS-2; hCS-B |
| NCBI Protein Information: | chorionic somatomammotropin hormone 2; lactogen; choriomammotropin; placental lactogen; chorionic somatomammotropin B |
| UniProt Protein Name: | Chorionic somatomammotropin hormone 2 |
| UniProt Synonym Protein Names: | Lactogen; Placental lactogen; PL |
| Protein Family: | |
| UniProt Gene Name: | CSH2 |
| UniProt Entry Name: | CSH2_HUMAN |
| Antibodies |
| CSH2 Antibody (PACO08628) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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