CSGALNACT2 Antibody (PACO25985)
- SKU:
- PACO25985
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CSGALNACT2 Antibody (PACO25985) |
| Antibody SKU: | PACO25985 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Chondroitin sulfate N-acetylgalactosaminyltransferase 2 protein (33-270AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: CSGALNACT2 antibody at 4µg/ml Lane 1: K562 whole cell lysate Lane 2: 293T whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: PC-3 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 63, 39 kDa Observed band size: 63 kDa . |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO25985 at dilution of 1:100. |
| Background: | Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid, (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. |
| Synonyms: | Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (EC 2.4.1.174) (Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2) (Beta4GalNAcT-2) (GalNAcT-2), CSGALNACT2, CHGN2 GALNACT2 |
| UniProt Protein Function: | GALNACT2: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Glycan Metabolism - chondroitin sulfate biosynthesis; Transferase; Membrane protein, integral; EC 2.4.1.174 Chromosomal Location of Human Ortholog: 10q11.21 Cellular Component: Golgi membrane; membrane; integral to Golgi membrane Molecular Function:acetylgalactosaminyltransferase activity; metal ion binding; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity Biological Process: chondroitin sulfate metabolic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; carbohydrate metabolic process; pathogenesis; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process |
| NCBI Summary: | This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q8N6G5 |
| NCBI GenInfo Identifier: | 60391915 |
| NCBI Gene ID: | 55454 |
| NCBI Accession: | Q8N6G5.1 |
| UniProt Secondary Accession: | Q8N6G5,Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6, B3KWL7, |
| UniProt Related Accession: | Q8N6G5 |
| Molecular Weight: | 38,440 Da |
| NCBI Full Name: | Chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| NCBI Synonym Full Names: | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| NCBI Official Symbol: | CSGALNACT2 |
| NCBI Official Synonym Symbols: | CHGN2; PRO0082; GALNACT2; GALNACT-2 |
| NCBI Protein Information: | chondroitin sulfate N-acetylgalactosaminyltransferase 2; beta 4 GalNAcT-2; chondroitin beta1,4 N-acetylgalactosaminyltransferase 2 |
| UniProt Protein Name: | Chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| UniProt Synonym Protein Names: | Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2; Beta4GalNAcT-2; GalNAcT-2 |
| Protein Family: | Chondroitin sulfate N-acetylgalactosaminyltransferase |
| UniProt Gene Name: | CSGALNACT2 |
| UniProt Entry Name: | CGAT2_HUMAN |
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