Name: CSGALNACT2 Antibody (PACO15718)
SKU: PACO15718
Availability: OutOfStock

Antibody Name:	CSGALNACT2 Antibody (PACO15718)
Antibody SKU:	PACO15718
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:2000-1:5000, IHC:1:25-1:100
Species Reactivity:	Human, Mouse
Immunogen:	Fusion protein of human CSGALNACT2

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO15718(CSGALNACT2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200).

Background:

This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. A related pseudogene has been identified on chromosome X. Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid, (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains.

Synonyms:

chondroitin sulfate N-acetylgalactosaminyltransferase 2

UniProt Protein Function:	GALNACT2: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:Glycan Metabolism - chondroitin sulfate biosynthesis; Transferase; Membrane protein, integral; EC 2.4.1.174 Chromosomal Location of Human Ortholog: 10q11.21 Cellular Component: Golgi membrane; membrane; integral to Golgi membrane Molecular Function:acetylgalactosaminyltransferase activity; metal ion binding; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity Biological Process: chondroitin sulfate metabolic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; carbohydrate metabolic process; pathogenesis; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process
NCBI Summary:	This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Dec 2012]
UniProt Code:	Q8N6G5
NCBI GenInfo Identifier:	60391915
NCBI Gene ID:	55454
NCBI Accession:	Q8N6G5.1
UniProt Secondary Accession:	Q8N6G5,Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6, B3KWL7,
UniProt Related Accession:	Q8N6G5
Molecular Weight:	38,440 Da
NCBI Full Name:	Chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Synonym Full Names:	chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Official Symbol:	CSGALNACT2
NCBI Official Synonym Symbols:	CHGN2; PRO0082; GALNACT2; GALNACT-2
NCBI Protein Information:	chondroitin sulfate N-acetylgalactosaminyltransferase 2; beta 4 GalNAcT-2; chondroitin beta1,4 N-acetylgalactosaminyltransferase 2
UniProt Protein Name:	Chondroitin sulfate N-acetylgalactosaminyltransferase 2
UniProt Synonym Protein Names:	Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2; Beta4GalNAcT-2; GalNAcT-2
Protein Family:	Chondroitin sulfate N-acetylgalactosaminyltransferase
UniProt Gene Name:	CSGALNACT2
UniProt Entry Name:	CGAT2_HUMAN