CSGALNACT1 Antibody (PACO04727)
- SKU:
- PACO04727
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CSGALNACT1 Antibody |
| Antibody SKU: | PACO04727 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human Beta-1,4-GalNAc-T. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CSGALNACT1; CHGN; GALNACT1; Chondroitin sulfate N-acetylgalactosaminyltransferase 1; CsGalNAcT-1; Chondroitin beta-1; 4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT-1 |
| UniProt Protein Function: | ChGn: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transferase; Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.174Chromosomal Location of Human Ortholog: 8p21.3Cellular Component: Golgi membrane; intracellularMolecular Function: acetylgalactosaminyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; glucuronosyltransferase activity; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; peptidoglycan glycosyltransferase activityBiological Process: chondroitin sulfate biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process; proteoglycan biosynthetic process; UDP-glucuronate metabolic process; UDP-N-acetylgalactosamine metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TDX6 |
| NCBI GenInfo Identifier: | 308153425 |
| NCBI Gene ID: | 55790 |
| NCBI Accession: | Q8TDX6.2 |
| UniProt Secondary Accession: | Q8TDX6,Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9, B2RBE4 |
| UniProt Related Accession: | Q8TDX6 |
| Molecular Weight: | 33,917 Da |
| NCBI Full Name: | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| NCBI Synonym Full Names: | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| NCBI Official Symbol: | CSGALNACT1 |
| NCBI Official Synonym Symbols: | ChGn; CSGalNAcT-1; beta4GalNAcT |
| NCBI Protein Information: | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| UniProt Protein Name: | Chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| UniProt Synonym Protein Names: | Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT-1 |
| Protein Family: | Chondroitin sulfate N-acetylgalactosaminyltransferase |
| UniProt Gene Name: | CSGALNACT1 |
| UniProt Entry Name: | CGAT1_HUMAN |
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