Description
Antibody Name: | CRIM1 Antibody (PACO19512) |
Antibody SKU: | PACO19512 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthetic peptide of human CRIM1 |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19512(CRIM1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO19512(CRIM1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor β family, such as bone morphogenetic proteins. |
Synonyms: | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
UniProt Protein Function: | May play a role in CNS development by interacting with growth factors implicated in motor neuron differentiation and survival. May play a role in capillary formation and maintenance during angiogenesis. Modulates BMP activity by affecting its processing and delivery to the cell surface. |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a transmembrane protein containing six cysteine-rich repeat domains and an insulin-like growth factor-binding domain. The encoded protein may play a role in tissue development though interactions with members of the transforming growth factor beta family, such as bone morphogenetic proteins. [provided by RefSeq, Nov 2010] |
UniProt Code: | Q9NZV1 |
NCBI GenInfo Identifier: | 119620831 |
NCBI Gene ID: | 51232 |
NCBI Accession: | EAX00426.1 |
UniProt Secondary Accession: | Q9NZV1,Q2M2G4, Q59GH0, Q7LCQ5, Q9H318 |
UniProt Related Accession: | Q9NZV1 |
Molecular Weight: | 113,738 Da |
NCBI Full Name: | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
NCBI Synonym Full Names: | cysteine rich transmembrane BMP regulator 1 |
NCBI Official Symbol: | CRIM1 |
NCBI Official Synonym Symbols: | S52; CRIM-1 |
NCBI Protein Information: | cysteine-rich motor neuron 1 protein |
UniProt Protein Name: | Cysteine-rich motor neuron 1 protein |
UniProt Synonym Protein Names: | Cysteine-rich repeat-containing protein S52 |
Protein Family: | Cysteine-rich motor neuron 1 protein |
UniProt Gene Name: | CRIM1 |
UniProt Entry Name: |