Description
Antibody Name: | CREB3L4 Antibody (PACO52654) |
Antibody SKU: | PACO52654 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Cyclic AMP-responsive element-binding protein 3-like protein 4 protein (13-133AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO52654 at dilution of 1:100. |
Background: | Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements (By similarity). |
Synonyms: | Cyclic AMP-responsive element-binding protein 3-like protein 4 (cAMP-responsive element-binding protein 3-like protein 4) (Androgen-induced basic leucine zipper protein) (AIbZIP) (Attaching to CRE-like 1) (ATCE1) (Cyclic AMP-responsive element-binding protein 4) (CREB-4) (cAMP-responsive element-binding protein 4) (Transcript induced in spermiogenesis protein 40) (Tisp40) (hJAL) [Cleaved into: Processed cyclic AMP-responsive element-binding protein 3-like protein 4], CREB3L4, AIBZIP CREB4 JAL |
UniProt Protein Function: | CREB3L4: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements. Belongs to the bZIP family. ATF subfamily.Protein type: Transcription factor; Endoplasmic reticulum; Membrane protein, integralChromosomal Location of Human Ortholog: 1q21.3Cellular Component: endoplasmic reticulum; Golgi apparatusBiological Process: positive regulation of transcription from RNA polymerase II promoter |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q8TEY5 |
NCBI GenInfo Identifier: | 74751463 |
NCBI Gene ID: | 148327 |
NCBI Accession: | Q8TEY5.1 |
UniProt Secondary Accession: | Q8TEY5,Q5T4L0, Q86YW6, D3DV62 |
UniProt Related Accession: | Q8TEY5 |
Molecular Weight: | 41,275 Da |
NCBI Full Name: | Cyclic AMP-responsive element-binding protein 3-like protein 4 |
NCBI Synonym Full Names: | cAMP responsive element binding protein 3 like 4 |
NCBI Official Symbol: | CREB3L4 |
NCBI Official Synonym Symbols: | JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP |
NCBI Protein Information: | cyclic AMP-responsive element-binding protein 3-like protein 4 |
UniProt Protein Name: | Cyclic AMP-responsive element-binding protein 3-like protein 4 |
UniProt Synonym Protein Names: | Androgen-induced basic leucine zipper protein; AIbZIP |
Protein Family: | Cyclic AMP-responsive element-binding protein 3-like protein |
UniProt Gene Name: | CREB3L4 |
UniProt Entry Name: | CR3L4_HUMAN |
Antibodies |
CREB3L4 Antibody (PACO08593) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |