CREB3L1 Antibody (PACO13412)
- SKU:
- PACO13412
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CREB3L1 Antibody (PACO13412) |
| Antibody SKU: | PACO13412 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human CREB3L1,OASIS |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | cAMP responsive element binding protein 3-like 1;CREB3L1;OASIS ; |
| UniProt Protein Function: | CREB3L1: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. Belongs to the bZIP family. ATF subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription factor; Membrane protein, integral Chromosomal Location of Human Ortholog: 11p11.2 Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; nucleus Molecular Function:sequence-specific DNA binding; chromatin binding Biological Process: transcription, DNA-dependent; unfolded protein response; regulation of bone mineralization |
| NCBI Summary: | The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box-B elements. [provided by RefSeq, Jun 2013] |
| UniProt Code: | Q96BA8 |
| NCBI GenInfo Identifier: | 74751763 |
| NCBI Gene ID: | 90993 |
| NCBI Accession: | Q96BA8.1 |
| UniProt Secondary Accession: | Q96BA8,Q8N2D5, Q96CP0, |
| UniProt Related Accession: | Q96BA8 |
| Molecular Weight: | 519 |
| NCBI Full Name: | Cyclic AMP-responsive element-binding protein 3-like protein 1 |
| NCBI Synonym Full Names: | cAMP responsive element binding protein 3-like 1 |
| NCBI Official Symbol: | CREB3L1 |
| NCBI Official Synonym Symbols: | OASIS |
| NCBI Protein Information: | cyclic AMP-responsive element-binding protein 3-like protein 1; BBF-2 homolog; old astrocyte specifically-induced substance; cAMP-responsive element-binding protein 3-like protein 1 |
| UniProt Protein Name: | Cyclic AMP-responsive element-binding protein 3-like protein 1 |
| UniProt Synonym Protein Names: | Old astrocyte specifically-induced substance; OASIS |
| Protein Family: | Cyclic AMP-responsive element-binding protein 3-like protein |
| UniProt Gene Name: | CREB3L1 |
| UniProt Entry Name: | CR3L1_HUMAN |
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