Description
Product Name: | CRBN Monoclonal Antibody |
Product Code: | CAB24651 |
Reactivity: | Human, Mouse, Rat |
Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC64184 |
Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | 293T, PC-3, A549 (Low expression control) |
Cellular Location: | Cytoplasm, Membrane, Nucleus, Peripheral membrane protein |
This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic cognitive disability. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CRBN (NP_057386.2). |
Sequence: | MAGEG DQQDA AHNMG NHLPL LPAES EEEDE MEVED QDSKE AKKPN IINFD TSLPT SHTYL GADME EFHGR TLHDD DSCQV IPVLP QVMMI LIPGQ TLPLQ LFHPQ EVSMV RNLIQ KDRTF AVLAY SNVQE REAQF GTTAE IYAYR EEQDF GIEIV KVKAI GRQRF KVLEL RTQSD GIQQA KVQIL PECVL PSTMS AVQLE SLNKC QIFPS KPVSR EDQCS YKWWQ KYQKR KFHCA NLTSW PRWLY SLYDA ETLMD RIKKQ LREWD ENLKD DSLPS NPIDF |
Synonyms: | MRT2, MRT2A |
Calculated MW: | 51kDa |
Observed MW: | 55kDa |