CPZ Antibody (PACO05567)
- SKU:
- PACO05567
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CPZ Antibody (PACO05567) |
| Antibody SKU: | PACO05567 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000 |
| Species Reactivity: | Human, Rat |
| Immunogen: | Synthesized peptide derived from the Internal region of human CPZ. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | CPZ; Carboxypeptidase Z; CPZ |
| UniProt Protein Function: | CPZ: Cleaves substrates with C-terminal arginine residues. Probably modulates the Wnt signaling pathway, by cleaving some undefined protein. May play a role in cleavage during prohormone processing. Belongs to the peptidase M14 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted; EC 3.4.17.-; Secreted, signal peptide; Protease; Extracellular matrixChromosomal Location of Human Ortholog: 4p16.1Cellular Component: proteinaceous extracellular matrixMolecular Function: zinc ion binding; metallocarboxypeptidase activityBiological Process: Wnt receptor signaling pathway; proteolysis |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the metallocarboxypeptidase family. This enzyme displays carboxypeptidase activity towards substrates with basic C-terminal residues. It is most active at neutral pH and is inhibited by active site-directed inhibitors of metallocarboxypeptidases. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q66K79 |
| NCBI GenInfo Identifier: | 296434423 |
| NCBI Gene ID: | 8532 |
| NCBI Accession: | Q66K79.2 |
| UniProt Secondary Accession: | Q66K79,O00520, Q96MX2 |
| UniProt Related Accession: | Q66K79 |
| Molecular Weight: | |
| NCBI Full Name: | Carboxypeptidase Z |
| NCBI Synonym Full Names: | carboxypeptidase Z |
| NCBI Official Symbol: | CPZ |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | carboxypeptidase Z; metallocarboxypeptidase Z |
| UniProt Protein Name: | Carboxypeptidase Z |
| UniProt Synonym Protein Names: | |
| Protein Family: | Carboxypeptidase |
| UniProt Gene Name: | CPZ |
| UniProt Entry Name: | CBPZ_HUMAN |
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