CPT1A Monoclonal Antibody (CAB22450)
- SKU:
- CAB22450
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | CPT1A Monoclonal Antibody |
| Product Code: | CAB22450 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51170 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse heart, Mouse liver, Mouse kidney, HepG2, MCF-7 |
| Cellular Location: | mitochondrial outer membrane, mitochondrion |
The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 520-720 of human CPT1A (NP_001867.2). |
| Sequence: | WDIPG ECQEV IETSL NTANL LANDV DFHSF PFVAF GKGII KKCRT SPDAF VQLAL QLAHY KDMGK FCLTY EASMT RLFRE GRTET VRSCT TESCD FVRAM VDPAQ TVEQR LKLFK LASEK HQHMY RLAMT GSGID RHLFC LYVVS KYLAV ESPFL KEVLS EPWRL STSQT PQQQV ELFDL ENNPE YVSSG GGFGP VADDG Y |
| Synonyms: | CPT1, CPT1-L, L-CPT1 |
| Calculated MW: | 88kDa |
| Observed MW: | 88kDa |
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