CPS1 Monoclonal Antibody
- SKU:
- CAB24810
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | CPS1 Monoclonal Antibody |
| Product Code: | CAB24810 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC63814 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:2000-1:5000, IHC-P 1:200-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | BeWo |
| Cellular Location: | Mitochondrion, Nucleus, nucleolus, Cell membrane |
The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1356-1482 of human CPS1 (NP_001116105.1). |
| Sequence: | KIPQK GILIG IQQSF RPRFL GVAEQ LHNEG FKLFA TEATS DWLNA NNVPA TPVAW PSQEG QNPSL SSIRK LIRDG SIDLV INLPN NNTKF VHDNY VIRRT AVDSG IPLLT NFQVT KLFAE AVQKS RK |
| Synonyms: | PHN, GATD6, CPSASE1 |
| Calculated MW: | 165kDa |
| Observed MW: | 165kDa |
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