CPO Antibody (PACO59700)
- SKU:
- PACO59700
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CPO Antibody (PACO59700) |
| Antibody SKU: | PACO59700 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Carboxypeptidase O protein (21-101AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescence staining of HepG2 cells with PACO59700 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Carboxypeptidase which preferentially cleaves C-terminal acid, c residues from peptides and proteins. Can also cleave C-terminal hydrophobic amino acid, , with a preference for small residues over large residues. |
| Synonyms: | Carboxypeptidase O (CPO) (EC 3.4.17), CPO |
| UniProt Protein Function: | CPO: Probable carboxypeptidase which may cleave proteins with C-terminal acidic residues. Belongs to the peptidase M14 family.Protein type: EC 3.4.17.-; Secreted, signal peptide; Protease; SecretedChromosomal Location of Human Ortholog: 2q33.3Cellular Component: extracellular spaceMolecular Function: metallocarboxypeptidase activity |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the metallocarboxypeptidase gene family. [provided by RefSeq, Jan 2011] |
| UniProt Code: | Q8IVL8 |
| NCBI GenInfo Identifier: | 74723635 |
| NCBI Gene ID: | 130749 |
| NCBI Accession: | Q8IVL8.1 |
| UniProt Secondary Accession: | Q8IVL8,Q2M277, Q7RTW7 |
| UniProt Related Accession: | Q8IVL8 |
| Molecular Weight: | 42,529 Da |
| NCBI Full Name: | Carboxypeptidase O |
| NCBI Synonym Full Names: | carboxypeptidase O |
| NCBI Official Symbol: | CPO |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | carboxypeptidase O |
| UniProt Protein Name: | Carboxypeptidase O |
| UniProt Synonym Protein Names: | |
| Protein Family: | Carboxypeptidase |
| UniProt Gene Name: | CPO |
| UniProt Entry Name: | CBPO_HUMAN |
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