CPNE8 Antibody (PACO22288)
- SKU:
- PACO22288
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | CPNE8 Antibody (PACO22288) |
| Antibody SKU: | PACO22288 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from N-terminal of human CPNE8. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using CPNE8 antibody. |
| Background: | May function in membrane trafficking. Exhibits calcium-dependent phospholipid binding properties By similarity. |
| Synonyms: | copine VIII; copine-8; |
| UniProt Protein Function: | CPNE8: a member of the copine protein family with calcium-dependent phospholipid binding properties. Copines are ubiquitously expressed, phospholipid-binding proteins that have been conserved through evolution. Highest expression of CPNE8 mRNA is seen in the prostate, heart, and brain. Fusion to AML1 in a t(12;21) translocation causes aggressive acute myelogenous leukemia. Two alternatively spliced isoforms have been described.Protein type: Unknown functionChromosomal Location of Human Ortholog: 12q12 |
| UniProt Protein Details: | |
| NCBI Summary: | Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene is one of several genes that encode a calcium-dependent protein containing two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q86YQ8 |
| NCBI GenInfo Identifier: | 115502379 |
| NCBI Gene ID: | 144402 |
| NCBI Accession: | Q86YQ8.2 |
| UniProt Secondary Accession: | Q86YQ8,Q2TB41, Q86VY2 |
| UniProt Related Accession: | Q86YQ8 |
| Molecular Weight: | 25,664 Da |
| NCBI Full Name: | Copine-8 |
| NCBI Synonym Full Names: | copine 8 |
| NCBI Official Symbol: | CPNE8 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | copine-8 |
| UniProt Protein Name: | Copine-8 |
| UniProt Synonym Protein Names: | Copine VIII |
| Protein Family: | Copine |
| UniProt Gene Name: | CPNE8 |
| UniProt Entry Name: | CPNE8_HUMAN |
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