COX7B2 Antibody (PACO13914)
- SKU:
- PACO13914
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | COX7B2 Antibody (PACO13914) |
| Antibody SKU: | PACO13914 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human COX7B2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human lymphoma tissue using PACO13914(COX7B2 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water and ATP. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7b (cytochrome c oxidase subunit VIIb polypeptide) and COX7b2 (cytochrome c oxidase subunit VIIb polypeptide 2) are 80 and 81 amino acid, proteins, respectively, which exist as components of the COX complex, therefore playing an important role in electron transport. A rare polymorphism in the COX7b2 gene at codon 26 may be linked to nasopharyngeal carcinoma (NPC), the most common head and neck cancer in southern China. |
| Synonyms: | cytochrome c oxidase subunit VIIb2 |
| UniProt Protein Function: | COX7B2: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIIb family.Protein type: Membrane protein, integral; Mitochondrial; OxidoreductaseChromosomal Location of Human Ortholog: 4p12Cellular Component: integral to membrane; mitochondrial respiratory chainMolecular Function: cytochrome-c oxidase activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TF08 |
| NCBI GenInfo Identifier: | 115527068 |
| NCBI Gene ID: | 170712 |
| NCBI Accession: | NP_570972.2 |
| UniProt Secondary Accession: | Q8TF08,Q32Q40 |
| UniProt Related Accession: | Q8TF08 |
| Molecular Weight: | 9,077 Da |
| NCBI Full Name: | cytochrome c oxidase subunit 7B2, mitochondrial |
| NCBI Synonym Full Names: | cytochrome c oxidase subunit VIIb2 |
| NCBI Official Symbol: | COX7B2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | cytochrome c oxidase subunit 7B2, mitochondrial; cytochrome c oxidase polypeptide VIIb2 |
| UniProt Protein Name: | Cytochrome c oxidase subunit 7B2, mitochondrial |
| UniProt Synonym Protein Names: | Cytochrome c oxidase polypeptide VIIb2 |
| Protein Family: | Cytochrome c oxidase |
| UniProt Gene Name: | COX7B2 |
| UniProt Entry Name: | CX7B2_HUMAN |
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