Description
Antibody Name: | COX7A2P2 Antibody (PACO23325) |
Antibody SKU: | PACO23325 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Synthesized peptide derived from internal of human COX7S/A2. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from rat heart cells, using COX7S/A2 antibody. | |
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using COX7S/A2 antibody. |
Synonyms: | Cytochrome c oxidase subunit VIIa 3; mitochondrial [Precursor]; COX7AP2; COX7A3; COX7AL2 |
UniProt Protein Function: | COX7A2: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase VIIa family.Protein type: Energy Metabolism - oxidative phosphorylation; Mitochondrial; EC 1.9.3.1; OxidoreductaseChromosomal Location of Human Ortholog: 6q12Cellular Component: mitochondrial respiratory chainMolecular Function: cytochrome-c oxidase activity |
UniProt Protein Details: | |
NCBI Summary: | Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009] |
UniProt Code: | O60397 |
NCBI GenInfo Identifier: | 8928009 |
NCBI Gene ID: | 1347 |
NCBI Accession: | O60397.1 |
UniProt Secondary Accession: | O60397,P14406 |
UniProt Related Accession: | O60397,P14406 |
Molecular Weight: | 11,841 Da |
NCBI Full Name: | Putative cytochrome c oxidase subunit 7A3, mitochondrial |
NCBI Synonym Full Names: | cytochrome c oxidase subunit VIIa polypeptide 2 (liver) |
NCBI Official Symbol: | COX7A2 |
NCBI Official Synonym Symbols: | VIIAL; COX7AL; COX7AL1; COXVIIAL; COXVIIa-L |
NCBI Protein Information: | cytochrome c oxidase subunit 7A2, mitochondrial |
UniProt Protein Name: | Putative cytochrome c oxidase subunit 7A3, mitochondrial |
UniProt Synonym Protein Names: | Cytochrome c oxidase subunit VIIa 3 |
Protein Family: | Cytochrome c oxidase |
UniProt Gene Name: | COX7A2P2 |
UniProt Entry Name: | COX7S_HUMAN |