Description
| Product Name: | COX7A1 Monoclonal Antibody |
| Product Code: | CAB21240 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC53426 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:20000, IHC-P 1:2000-1:6000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | A549, 293T, Mouse heart, Rat heart, Rat skeletal muscle |
| Cellular Location: | Mitochondrion inner membrane |
Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-79 of human COX7A1 (NP_001855.1). |
| Sequence: | MQALR VSQAL IRSFS STARN RFQNR VREKQ KLFQE DNDIP LYLKG GIVDN ILYRV TMTLC LGGTV YSLYS LGWAS FPRN |
| Synonyms: | COX7A, COX7AH, COX7AM |
| Calculated MW: | 9kDa |
| Observed MW: | 9kDa |