COX6B2 Antibody (PACO14280)
- SKU:
- PACO14280
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | COX6B2 Antibody (PACO14280) |
| Antibody SKU: | PACO14280 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human COX6B2 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14280(COX6B2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: A549 cells, Primary antibody: PACO14280(COX6B2 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO14280(COX6B2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. Localized to the intermembrane space, COX6b2 (Cytochrome c oxidase subunit 6B2), also known as Cytochrome c oxidase subunit VIb isoform 2 and Cancer/testis antigen 59, is a 88 amino acid, mitochondrial protein that is responsible for joining the two COX monomers to form the COX dimer. COX6b2 is specifically expressed in testis and is found to be upregulated in certain cancer cell lines. |
| Synonyms: | cytochrome c oxidase subunit VIb polypeptide 2 (testis) |
| UniProt Protein Function: | COX6B2: Connects the two COX monomers into the physiological dimeric form. Belongs to the cytochrome c oxidase subunit 6B family. |
| UniProt Protein Details: | Protein type:Oxidoreductase; Cancer Testis Antigen (CTA); Mitochondrial Chromosomal Location of Human Ortholog: 19q13.42 Cellular Component: mitochondrial crista; mitochondrial intermembrane space Molecular Function:cytochrome-c oxidase activity |
| UniProt Code: | Q6YFQ2 |
| NCBI GenInfo Identifier: | 74738324 |
| NCBI Gene ID: | 125965 |
| NCBI Accession: | Q6YFQ2.1 |
| UniProt Related Accession: | Q6YFQ2 |
| Molecular Weight: | 11kDa |
| NCBI Full Name: | Cytochrome c oxidase subunit 6B2 |
| NCBI Synonym Full Names: | cytochrome c oxidase subunit 6B2 |
| NCBI Official Symbol: | COX6B2 |
| NCBI Official Synonym Symbols: | CT59; COXVIB2 |
| NCBI Protein Information: | cytochrome c oxidase subunit 6B2 |
| UniProt Protein Name: | Cytochrome c oxidase subunit 6B2 |
| UniProt Synonym Protein Names: | Cancer/testis antigen 59; CT59; Cytochrome c oxidase subunit VIb isoform 2; COX VIb-2; Cytochrome c oxidase subunit VIb, testis-specific isoform |
| Protein Family: | Cytochrome c oxidase |
| UniProt Gene Name: | COX6B2 |
| UniProt Entry Name: | CX6B2_HUMAN |
| Antibodies |
| COX6B2 Antibody (PACO08551) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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