COX5A Polyclonal Antibody
- SKU:
- CAB24500
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | COX5A Polyclonal Antibody |
| Product Code: | CAB24500 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, Mouse brain, Mouse heart, Rat brain |
| Cellular Location: | Mitochondrion inner membrane |
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human COX5A (NP_004246.2). |
| Sequence: | MLGAA LRRCA VAATT RADPR GLLHS ARTPG PAVAI QSVRC YSHGS QETDE EFDAR WVTYF NKPDI DAWEL RKGIN TLVTY DMVPE PKIID AALRA CRRLN DFAST VRILE VVKDK AGPHK EIYPY VIQEL RPTLN ELGIS TPEEL GLDKV |
| Synonyms: | COX5A, COX, COX-VA, VA, cytochrome c oxidase subunit 5A |
| Calculated MW: | 16kDa |
| Observed MW: | 15kDa |
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