Description
| Antibody Name: | COX18 Antibody (PACO08545) |
| Antibody SKU: | PACO08545 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Human COX18 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | COX18 cytochrome c oxidase assembly homolog (S. cerevisiae);COX18;COX18HS;FLJ38991;MGC126733 ; |
| UniProt Protein Function: | COX18: Required for the insertion of integral membrane proteins into the mitochondrial inner membrane. Essential for the activity and assembly of cytochrome c oxidase. Plays a central role in the translocation and export of the C-terminal part of the COX2 protein into the mitochondrial intermembrane space. Belongs to the OXA1/ALB3/YidC family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Mitochondrial; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 4q13.3Cellular Component: integral to mitochondrial inner membraneMolecular Function: protein transporter activityBiological Process: protein transport; protein insertion into mitochondrial membrane; respiratory chain complex IV assembly |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a cytochrome c oxidase assembly protein. The encoded protein is essential for integral membrane protein insertion into the mitochondrial inner membrane. It is also required for cytochrome c oxidase assembly and activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q8N8Q8 |
| NCBI GenInfo Identifier: | 38372495 |
| NCBI Gene ID: | 285521 |
| NCBI Accession: | Q8N8Q8.1 |
| UniProt Secondary Accession: | Q8N8Q8,Q2PB66, Q2PB67, Q2PB68, Q49B97, Q6IPP9 |
| UniProt Related Accession: | Q8N8Q8 |
| Molecular Weight: | 333 |
| NCBI Full Name: | Mitochondrial inner membrane protein COX18 |
| NCBI Synonym Full Names: | COX18 cytochrome c oxidase assembly factor |
| NCBI Official Symbol: | COX18 |
| NCBI Official Synonym Symbols: | COX18HS |
| NCBI Protein Information: | mitochondrial inner membrane protein COX18; cytochrome c oxidase assembly homolog 18; cytochrome c oxidase assembly protein 18 |
| UniProt Protein Name: | Mitochondrial inner membrane protein COX18 |
| UniProt Synonym Protein Names: | Cytochrome c oxidase assembly protein 18 |
| Protein Family: | Mitochondrial inner membrane protein |
| UniProt Gene Name: | COX18 |
| UniProt Entry Name: | COX18_HUMAN |