Description
system_update_alt Datasheet
| Product Name: | COTL1 Antibody |
| Product Sku: | CPAB0607 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human COTL1 mAb, clone PAT1D6AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human COTL1 protein 1-142 amino acids purified from Ecoli. |
| Clone: | PAT1D6AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | COTL1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG2b |
| Background: | Coactosin-like protein (COTL1) is one of the numerous actin-binding proteins which regulate the actin cytoskeleton. COTL1 binds F-actin, it also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. COTL1 binds to F-actin in a calcium-independent way and has no direct effect on actin depolymerization. |
| Synonyms: | Coactosin-like protein, COTL1, CLP, FLJ43657, MGC19733. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |